Sunday, 19 April 2015

topic 2 introduction to immunology



What means by immunology actually ? I concluded that immunology focuses on the human body's built-in defense system. In a healthy person, the immune system helps the body fight infection by rejecting foreign viruses and bacteria. The key primary lymphoid organs of the immune system are thymus and bone marrow, and secondary lymphatic tissues such as spleen, tonsils, lymph vessels, lymph nodes, adenoids, and skin. There are 3 lines of body defense system :
a)external physical barrier –skin,mucos membrane,normal microbiota
b)internal barrier-phagocytic cell, inflammation and fever
c)specific immune response-humoral response and humoral immune
therefore, we can differentiate between the non-specific annd specific immune response. their characteristic shown the differences between the non specific and non specific immune response which is non-specific immune response is natural immune system , without memory and non specific. While specific immune response is specificity,inducibility,memory,distinguish self and non-self. There are two type of non-specific immune response :
Internal innate immunity-2 line defense-physiological barrier,phagocytosis,inflammation
External innate immunity-1 line defense-skin, mucos membrane and normal microbiota
we need to know that an antigen need to have this features:
-high molecular weight
-complexity
-soluble
-foreigness
this is differences between the antigen and antibody


Humoral (Antibody-Mediated) Immunity
-Found in body fluids.
-Antibodies are made by plasma cells (activated B lymphocytes) in response to specific antigen.
Cell-Mediated Immunity
-T cells have antigen receptors but don’t make antibodies – lyse target cells directly.

-Cell-mediated reactions primarily respond against intracellular viruses, multicellular parasites, transplanted tissue and cancer cells.
after the lecture we all conclude all the mechanism of different types of immunity in this whiteboard
this mind map is very helpful in order to understand in systematic ways in immunology .After learn on this topic i know that Immune system keep us safe from infection and diseases. It helps us keep ourselves healthy.  Any disease that causing bacteria that enters our body is prevented from causing any damage to the body as the immune system deals with it. We know that every single breath that we inhale, every drop of water we drink or the every bite of food we eat, all contains germs and we are vulnerable to attack by germs. 

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